Summary - Health and Fitness

Just when you think you have your weight under control; menopause rains on your parade. Why is weight gain and menopause synonymous? Your body produce

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s less estrogen, and instead of the fat being stored around the hip area; it proceeds directly to the stomach area.

In addition, the risk for diabetes

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

, high cholesterol and cardiovascular disease becomes a factor. Wait; it gets worse. If you are predisposed to high levels of cholesterol, losing estro

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

gen, which controls the levels of cholesterol, increases.

Thus, weight gain, though not directly caused by menopause, is a product of over-eating. As

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ou age, fewer calories are needed; you tend to exercise less; and if you happen to give up smoking, or are plagued with anxiety or depression, you find

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

whatever comfort you can in food.

Then the answer in reducing weight gain is to eat less and exercise more. Instead of a high daily caloric intake, r

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

educe it to a maximum of 1500 calories a day. A healthy diet regimen of fruits, vegetables, legumes, fish, low-fat diary and very lean meat can make qu

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ite a difference. Since calcium is so important during menopause be sure to get an adequate supply from fat-free cheeses, fat-free milk and light or fa

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

-free sour cream

In addition, increase your fiber intake and reduce liquids containing alcohol and caffeine. Reduction of alcohol and caffeine will al

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

so slow up the skin wrinkling process. More importantly, less fat in your diet is the key. Exercise regularly; this increases your good cholesterol and

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

reduces your bad cholesterol. It also prevents the possibility of diabetes, osteoporosis and other diseases. Because your metabolic rate lowers with a

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ge, exercise will raise the level which will inhibit your need to eat.

While there are other methods you can utilize such as hormone replacement thera

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

y, there are some studies which suggest the side effects associated with this course of action may not be desirable. However, if it is determined you h

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ave high cholesterol, either through no fault of your own, genetics or due to weight gain after menopause; there are specific medications which can low

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

er your cholesterol significantly. One of the most popular is Lipitor; and the other is Crestor. A routine blood test can determine your HDL and LDL l

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

evels, as well as your triglyceride count. There are also many over the counter cholesterol lowing products. Undoubtedly, your doctor will recommend e

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ther medication, or advise you to embark on a diet and exercise regimen.

Take comfort in the knowledge that your mom did not have the benefit of these

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

medical breakthroughs; she not only went through menopause, but did not need any medical intervention. Perhaps she gained weight, or maybe she did not

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

. Either way, she muddled through. While menopause is a fact of life; it does not have to be the end of it. Although we can not do much to decrease th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e affects; we can do a great deal to overcome the weight gain associated with it. Take the path of least resistance; begin a healthy diet program today

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Summary - Weight Gain Due To Menopause Is Not Set In Stone

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