Summary - Health and Fitness

Quitting smoking is not as easy as we think it is. It is not so difficult either, if you really want to quit. The real challenge is to make up your

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

mind to quit this habit. The moment you take it up as a challenge it is half done. Normally we do not take it seriously and assume that we can quit

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

it any time,but that time never comes unless we really want to quit.

What are the reasons that we start smoking in the first place. People have dif

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ferent reasons to start smoking . A teenager normally starts smoking to feel grown up. Actually he stops his growth the moment smoking becomes his

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

abit. Nicotine has a peculiar quality. The more you have nicotine the more you crave for it. Its reverse is also true. The less you smoke the lesser

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

you feel like smoking. Now the real question is how to quit it, if we get addicted to it. I have experienced the kind of withdrawal symptoms one ha

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

s to go through before quitting this habit for good. Here are some simple tips I have found to be very effective .

1. As I said that the more you s

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

moke the more you feel like smoking, we should first make a list of benefits and ill effects of cigarette. The only benefit of smoking is that we ge

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

a high temporarily. Within half an hour of the last puff, the high is no longer there. We can make a long list of ill effects of smoking. I need no

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t emphasise, no matter who you are, ill effects of smoking are always on the higher side than the benefits, no matter how you justify you smoking ha

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

bit. Now ask yourself if it is really worth to spend money to ruin your health and vitality. I am sure your answer will be no.

2. Once the list is

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

complete pin it up somewhere in your house or work place so that you can easily have look at it whenever you wish. Read the ill effects whenever yo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

have time, and convince yourself that you really want to get rid of this habit , as the benefits in terms of saving money and health is one of the

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

greatest motivating factor. Calculate how much you can save if you do not smoke. It is always a good amount.

3. Cigarette reduces oxygen carrying c

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

apacity of lungs, but the good news is it can be increased if we start exercising regularly. Breathing exercises are the best to increase our lungs'

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

oxygen carrying capacity. Try to take deep breath when you feel like smoking . It reduces the urge to smoke as you take more oxygen in place of nic

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tine.

4. You can also take something else in place of cigarette. Water is the best option, drink a few glasses of water when it is time to smoke. I

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

t will kill your urge to smoke for a few hours. Drink as much water as you can because it not only reduces your urge to smoke but also cleanses your

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

digestive and other systems.

5. Try quitting it cold turkey instead of quitting it slowly. Quitting slowly means you have not been able to convinc

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e yourself that it will make you more healthy and wealthy. So repeat the point 1 and 2 mentioned above and once you are convinced start with point 3

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Breathing is powerful! It’s not only the way we keep our bodies functioning, but we can use it as a major influencing factor on our state of mind. Most of us don't breathe deeply enough, but the simple act of breathing correctly can help us reduce stress and tension.

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