Summary - Health and Fitness

If you've just finished a gruelling set and discover that you've left a nice

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

little puddle on the cushion/cardio machine big enough for your pet fish to s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

wim in it, please, PLEASE, PLEAAAASE wipe it off! There is nothing worse than

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

lying on a bench with the previous user’s sweat all over it.

Have you ever

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

wondered - what is sweat? Sweat and urine are both wastes from met

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

abolic activities and consists of water, salts, and urea. So, yes, sweat & ur

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ine are made basically from the same 'ingredients' (except in different conce

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ntrations). Now, do you feel like lying down and rubbing your face in another

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

person's urine? I didnt think so.

I've heard some people say that it doesn'

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t matter because their sweat will evaporate and therefore isn't a problem - b

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ut the truth is that only the WATER evaporates, leaving behind the yucky part

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s ready for the next person to unknowingly wet it with his/her own sweat and

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

get it all over them. Think of it as "instant urine" the next time you see s

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

omeone walk away from a pool of sweat with that excuse.

So.. the next time y

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ou use the equipment at your gym and leave behind a little puddle of your jui

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ces - PLEASE wipe it off before you go. I don't want to wipe your sweat. Towe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ls help you keep your sweat to yourself!

If you don't carry a towel, check t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

o see if your gym does (most gyms do). Fitness first keeps many towels togeth

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

er with a spray bottle of disinfectant (in this case, dettol). Spray it on th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e towel, then wipe.

I'm off to the gym now, with a towel to wipe my sweat. ;

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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