Summary - Health and Fitness

Diabetes!!!

Open your eyes to the catastrophic effects of Diabetes. The mere thought of Diabetes

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

brings so many questions and fears into our mind .Few people realize that thorough understanding

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and knowledge about diabetes can help tremendously in effective long term management. Diabetes i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s actually deficiency of Insulin(A Hormone secreted by small gland called Pancreas) which convert

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s sugar into energy) or the low ability of the body to use insulin. Thus glucose levels in blood

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tend to remain persistently raised. Diabetes is responsible for development of various complicati

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ons later in life. Diabetes welcomes Heart Diseases too like heart attacks and strokes (Double Tr

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ouble). Alone in US, more than 16 million people are suffering from Diabetes. People who are suff

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ering from Diabetes are at more risk to Heart problems and Kidney Failures. Diabetes and its side

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

effect occur among people of all ages.

What actually happens?

With the lack of Insulin in the

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

body, glucose and fats are not converted into energy and they remain as it is the Bloodstream and

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

with time contribute to Health diseases.

You can be Diabetes victim due to following reasons

a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

) Obesity definitely leads to Diabetes .

b) Individuals with impaired glucose tolerance or have

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

high fat content in their blood

c) It can get transferred to you through your parents or ancesto

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

rs.

d) Women who deliver babies weighing more than 9 pounds are susceptible to Diabetes.

e) Cer

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tain ethnic groups are more prone to Diabetes. Eg Mexican, Puerto Rican Americans and Cuban Ameri

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

cans can easily develop Diabetes.

Signs of Diabetes!!

a) Weakness and Fatigue

b) Frequent Thir

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

st and urination

c) Quick loss of weight

d) Feeling hungry

e) Blurring of vision

g) frequent

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

infections

h) numbness in limbs

Learn prevention of diabetes , special tips for fighting diabet

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

es and various complications because of diabetes at http://www.weightloss-health.com/Diabetes2.ht

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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