Summary - Health and Fitness

You might be surprised to know that skin is the largest organ in human body. It is a kind of sheath that separates us from the outer environment. It protects our internal organs from getting exposed to the harsh climatic condition pravelling outside. Any problem in skin or any kind of infection to the skin can causes threat to the internal organs. It helps in keeping our vital organ from hanging outside the body getting infected very easily. It also helps in maintaing body temperature. More importantly it helps us in perceiving sensation of touch.

According to modern sciences skin is made up of three layers. Named epidermis the outer layer, dermis the middle layer and subcutaneous fat the i

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nner layer. Ayurveda believes that skin has six layers.

Epidermis is the outer most layer of the skin and is the part of the skin, which is visible with our normal eyes. This layer of skin keeps on producing new cells, as 30000 to 40000 cells are lost every minute. It contains a very important content name melalin that is a very talked about things now a days. Melalin imparts colour to our skin. More the melalin content darker is the complexion. Actually melanin is a protective device of your skin that helps you to protect from sunburns and very harmful ultraviolet rays or more commonly called UV rays. This is the reason tanning occurs in people who get exposed to sun. But melalin productio

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is not enough to give all round protection to protect skin from dehydration and cancerous cell production. Important thing about epidermis is that it is composed of dead cells hence is non vascular i.e. it does not have blood supply and nervous supply.

Second is the dermis layer that lies below the epidermis. As it is beneath the epidermis hence dermis is not visible. Dermis serves very important function in the protective and perceptive role that skin plays. It serves many functions, as it possesses nerves ending, vascular supplies and glands (both oil or sebaceous glands and sweat glands). Due to presence of these factors we can perceive the touch sensation. Vascularity to the skin initi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ates in dermis and hence helps in providing proper nourishment to the skin cells. Dermis also contains sebaceous glands or more commonly called oil gland, which helps our skin in lubrication thus helping it from catching any infection. It makes our skin work as raincoats therefore help skin from getting sogged and swelled away in water. Sweat glands play a very important role in our life. Most important of all is that it helps in maintaing our body temperature; secondly it plays an excretory role by excreting out harmful toxins that might have formed in our body; thirdly it helps in protecting our body from microorganism as it possess antibacterial properties.

Third and the most important o

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

all the layers is the subcutaneous fatty layer. Its role is to work as a shock absorber in he body and to maintain body heat from getting transferred to outside temperature. It also helps in holding internal organs tightly as it is present beneath the skin. This also contains a very peculiar feature that only mammals possess i.e. hair follicles. This layer is full of hair follicles out of which hair grows out. Nourishment of hairs depends upon the sebaceous glands, which opens into the hair follicle thus proving it with shine and nutrients.

Types of skins

It is really very essential to know the kind of skin you possess, as right care of skin can help in reducing any skin problems a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

d avoid diseases. There are mainly 5 types of skin: -

1. Normal skin: It not a commonest kind of skin. It is soft, smooth, velvety and evenly textured skin with no flaky dead cells and no pores visible. Proper distribution of oil and moisture is there that makes it a balanced skin i.e. not excessively dry and not excessively greasy. It is clear and free from blemishes

2. Dry skin: Skin is said to be dry, when skin is dull, patchy, reddened and flaky especially around eyes. Dry skin may cause formation of fine lines on cheeks, under eyes and corners of mouth. These conditions happen when oil or sebaceous glands are not supplying good nourishment and lubrication to the skin. I

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

f proper care is not given to the skin then it may lead to initiation of wrinkles in early age.

3. Oily or greasy skin: This kind of skin is thick, dull in colour and shiny in appearance. Due to over secretions of oils or sebum through oil gland, makes skin pores open and skin becomes sticky, which attracts dirt and dust from the environment. Due to this tendency, dirt and dust particles blocks the skin pores which are already widely open in oily skin leads to problems like black head, white head, acne and other skin related problems.

4. Combination skin: Commonly seen skin texture which is the combination of two kind of skin i.e. some of the skin area is dry and some of the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rea is oily. Usually it follows the pattern of “T” i.e. the greasy part is usually the portion which is vertical to nose crossing nose (nose, mouth and chin) and horizontal on fore head and hence referred to as “T-Zone”. The area left i.e. cheeks is comparatively dry.

5. Sensitive skin: This kind of skin is very sensitive to any change in environmental conditions or any kind allergies, which may be caused due to procedures like bleaching, makeup’s and other external applications.

How to know that what type of skin you possess

It is a very simple method to know that what kind of skin you possess by following procedure mentioned below.

Whenever you wake up in morning, wipe yo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

r face with dry tissue soon after leaving your bed. If you find oil on that tissue, you possess oily or greasy skin. If you find grease on the center panel then you possess combination skin. If there is no grease at all then you either have dry or normal skin.

Now to check weather your skin is dry or normal. Just do one thing, wash your face with non-greasy soap and water. If you are left with the feeling of stretchiness and tightness on skin then you possess dry skin otherwise you have normal skin. If in daily routine you easily get skin allergies, rashes, itches and boils then your skin supposed to be sensitive

Our skin faces mainly three kinds of troubles

1. Firstly disease cau

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

sed directly to skin from external source.

This includes diseases that directly infect the skin from outside for example fungal infection in early stages etc

2. Secondly disease caused due to systemic disorders. This is the second category of the disease, which is caused due to systemic infection in the body. For example leprosy, psoriasis

3. Thirdly it may represent mere symptom of another disease. In this skin is the mere face that represents the symptom of any disease prevailing in the body. For example loosening of skin, which might be caused by dehydration.

How to make skin to happy so that it may remain healthy and glows with shine.

1. Protect your skin from over exposure

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

of sun by using sunscreens

2. Carry an umbrella or a cap with you when overexposed to external environment

3. Don’t smoke and drink excessively

4. Wash your skin gently and with lots of care

5. Moisturize your skin regularly

6. Shave with care and softly. Only shave in direction of hair growth

7. Use of good skin cleansers and toners regularly to open up blocked pores.

8. Drink lots of water and fresh fruit juices

9. Eat healthy food and avoid junk food.

10. Avoid use of chemicals on your skin

Inspite following these measures if you are not able to achieve the healthy and good skin then you must read below.

Here are some herbal remedies that is the answer to all your problems

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

enefits of neem on skin

· Neem is a wonder herb. Since early times neem is known for its wonderful properties and marvelous results on skin. It works as blood purifier and is very helpful in eradicating toxins from the blood that are supposed to cause harm to the skin.

· Local application of neem powder or neem oil has miraculous results. It is a famous anti microbial herb, it renders all the microorganisms inactive therefore helping in proper healing of wound without causing any infections and septic conditions

· Good results have been seen on skin problems like acne and blemishes. It helps in disinfecting the hair follicles and helps in eradicating the particle which is the main cul

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

prit in blocking the pore

· Taking bath of neem leaves socked water helps our body to counter mild infections, which our body might get in day-to-day activity

· Neem helps in early healing of burns and injuries that might also helps in fading of scars that are left after the any injury

· Tropical application and internal use of neem makes us relieved from eczema and even ringworms

· Neem is very helpful in providing internal glow to the skin by providing natural supplements that are required for good and healthy skin

· Neem is extensively used in hair fall and early graying of hairs with very satisfying results.

· It also find its application in dandruff and in lice growth

· Neem is h

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lpful in lighting dark circles which are usually caused due to life style disturbances

Know more about Benefits and Uses of Neem on Skin Care

Effects of Tulsi, the holy basil on skin

· Tulsi behave as an anti-bacterial and anti-fungal agent thus helps in eradicating any of the microorganisms developing on the wound and the skin.

· Tulsi is a wonderful blood purifier that helps in eradicating any toxins circulating in blood and helps us from any kind of foreign invasion there fore helps in protecting our skin from acne and other skin infections.

· It helps in normalizing our digestive system thus helpful in tre

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ting cause by which dark circles are caused.

· Tulsi is helpful in skin conditioning by improving blood circulation thereby helping each and every cell to get its part of nutrition and oxygen that helps in glowing skin

· Tulsi works as a powerful antioxidant thereby helps in preventing early aging signs and makes the skin young as never before

Know more about Benefits and Uses of Tulsi on skin care

Wheat grass and its effects on skin

· Wheat grass has been used since ages as it is helpful in providing required vitamins and minerals that are very helpful in nourishing skin and helps it to look healthy

· Due t

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

o presence of vitamin E in wheat grass, it helps in preventing aging and also helps in maintaing shine on the skin.

· Vitamin E also helps in preventing dark circles around eyes

· It is a good remedy in any skin disorder, as it possesses the cold potency, which is helpful in curbing skin disease that are of hot potency.

· Super oxide dismutase (SOD) present in wheat grass helps in slowing the aging process of cell thus gives the property of rasayan to wheat grass

· Alanine, an amino acid helps in promoting blood formation there fore helpful in formation of RBC (red blood corpuscles), WBC (white blood corpuscles), blood platelets etc. which are helpful in providing proper nourishment and

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rotection to cell from any foreign invasion

· Vitamins A present in wheat grass is very useful in improving vision of eyes therefore helping in providing proper nourishment to the skin under eyes preventing dark circles and sagging down of skin

· Iron is helpful in hemoglobin production therefore is helpful in increasing oxygen carrying capacity of blood and is helps in imparting pinkish colour to the skin

Amla and its benefits on skin

· It is very helpful in skin diseases as it has sheet virya (cold potency), it inhibits pitta dosha and thus helps in getting relief from it as all the skin disorders are caused by pitta dominance.

· Regular use of Amla promotes glow on skin and de

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ays wrinkles or loosening of skin. Good results have been found in eczema.

· Its internal use as well as its local application on scalp gives good results in hair loss as it provides nourishment to the skin on head (scalp).

· It stimulates hair follicles thus promoting hair growth and also improves texture of the hair.

· It also prevents premature graying of hairs and dandruff, which is flaking of dead cells of the scalp.

· Indian women generally use Amla to wash their hairs, which act as natural hair conditioner as it helps in providing good nourishment and also helps in normalizing blood supply

· It is helpful in making skin glow and works as an antioxidant therefore prevents wrinkles

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

and loosening of skin.

Know more about Benefits and Uses of Amla on skin care

Aloe vera: a skin specialist herb

Aloe vera is an herb extensively used in enhancing beauty in natural way.

· Aloe vera is known to help in condition known as dermatitis (an inflammatory disease of the skin) therefore helps in relieving from it

· It stabilizes digestive system and therefore is very essential in providing proper nourishment to the skin.

· Being an herb of cold potency, it helps in fighting against any skin diseases that are caused by pitta related disorders

· It works as magic in burn cases and researches have pro

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ed its efficacy in healing wounds faster than any thing

· It is helpful in erasing blemishes and dark spots on face generally caused after pregnancy.

· It helps in fighting with acne and other allergic disorders of skin thereby making pores clear and healthy

· Helps in lightening of the skin colour, as it helps in fighting extra amount of melalin that has been produced in body

· It works as an antioxidant therefore helps in fighting with the age related changes that has occurred with growing age

· Helps in slowing down the wrinkles developing on the skin.

· Helps in increasing circulation of blood thus facilitating easier oxygen exchange between the cells thus providing them nourishmen

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Summary - Benefits and Uses of Neem, Tulsi, Wheat Grass and Amla on Skin Care

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