Summary - Health and Fitness

Sterility is the condition in which the person is totally biologically incapable to produce children. It is also known as infertility. Sterility is always spoken of as the problem of a couple rather than of an individual. The problem can be of eith

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

er the male or the female partner, so in general, we say that the couple suffers from sterility. One of the preliminary steps in treating infertility is to determine whether the problem lies with the male or the female partner.

There are two types

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

of sterility or infertility seen in people. The first type is known as primary sterility. This is when the couple has never conceived a child. The second type, known as secondary sterility occurs when the couple has conceived a child, but has had a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

miscarriage. Primary sterility can be due to the male or the female partner; but secondary sterility is only due to problems with the woman’s reproductive system.

Dietary Guidelines for the Treatment of Sterility

Sometimes the problem is

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ith the food habits of the person. The following dietary guidelines must be obeyed by men and women who are unable to bear children.

- All milk products are found to be very good for bearing children. Drinking on glass of pure milk before the sexu

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

l activity always helps. This is found to be more effective in the male. This explains the Indian tradition of the bride giving the groom a glassful of milk on the first wedding night.

- Males suffering from sterility must not consume more of sali

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ne, sour, pungent and bitter foods. Foods that are sweet and astringent in taste are good. Sweet dishes prepared in milk are the best.

- Females suffering from sterility must avoid alkaline and pungent foods. Instead, they must take sweet foods an

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

fruits in large quantities.

- Eggs are very good for promoting conception in both men and women.

- Rice is better than wheat for sterile couples. Women who are not able to conceive must be given an all-rice diet.

- Ghee is the only acceptable f

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t for sterile couples.

- Honey is considered to be good. It is also effective in several problems of the reproductive system in both men and women.

- Nuts are very good for men who have a low sperm count. Groundnuts and almonds top the list.

- P

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

eople who have sterility problems must never keep their stomachs empty for a long period of time.

Ayurvedic Treatments for Sterility

For Sterile Women

Bala is the herb which is mostly prescribed for sterile women. Externally, it is

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

used as a douche. For this purpose, its root is boiled in oil and milk and then used with lukewarm water. Internally, it is used in the form of medicated oil taken along with milk.

Phala ghrita is also very commonly prescribed. This is given in do

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

es of two teaspoons twice daily when the stomach is empty. Milk is the vehicle used for phala ghrita. Other medicines used are Vanga bhasma and Shilajit. Shilajit is very well-known for its aphrodisiacal properties in both men and women. The dosage

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

of Shilajit is also one teaspoon twice a day.

For Sterile Men

The root of the Ashwagandha plant is most important for the treatment of sterility in men. Its root is dried to kill its smell of horse urine, then powdered and taken in a cup

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

f milk. The ratio is one teaspoon of Ashwagandha powder in one cup of milk. It is to be taken twice every day. Sugar can be mixed in it. Some Ayurvedic doctors also use Ashwagandharishta, which is a preparation of Ashwagandha in alcohol.

Makardhwa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

a is another important medicine. Makardhwaja is prepared by mixing gold, mercury and sulfur in a careful proportion. It is given in quantities of 125 milligrams twice daily on an empty stomach. The vehicle used is butter and sugar can be added for

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

flavoring it.

Home Remedies for Sterility

- Grind the aerial root of a banyan tree to a fine powder. Collect about 10 grams of this powder. Put this powder in half a liter of milk and boil it. When about 200 milliliters are left, remove it

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

from the flame and strain it. Mix sugar and honey in it. The woman must have this everyday from the fifth or seventh day of the commencement of the periods. Continue having this milk daily for ten days hence. This is considered to be the most effec

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ive remedy to make infertile women conceive.

- For women who are keeping normal health, but are still unable to conceive, the following remedy is found to work. Mix Shatavari choorna in ghee or milk and drink it on a daily basis before retiring fo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

r the day. This solves all the problems of the reproductive system and also makes it possible for the women to conceive.

- After every meal, the woman must take an areca nut (supari). This is effective in increasing fertility.

- Sterile couples m

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

st not overindulge in sexual activity. Restraint must be had, as it will improve the quality of the male sperm.

- Obesity is one of the leading causes of sterility. Hence, enrolling yourself in a weight-loss program will also help to bear children

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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