Summary - Reference and Education

One of the great triumphs of 19th century science was the development of electromagnetic the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ory. Devlepment of the theory began with Benjamin Franklin's experiments with static electri

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ity in 1748 and culminated with Maxwell's four equations, derived in 1864, which explain all

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

electromagnetic phenomena including electromagnetic waves.

For hundreds of years, electric

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ty and magnetism were quite mysterious forces, thought to be separate. Beginning in the 18th

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

century, several scientists experimented with electricity including Franklin, Coulomb, Volta

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

, Ampere, Faraday, and Maxwell. In 1748, Franklin discovered that there were two types of el

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ctric charge, positive and negative, and that like charges repel and opposite charges attrac

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

. Coulomb made this law mathematically precise. In 1800, Volta discovered the principle behi

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nd the battery and was able to use them to produce electric currents. In 1819, Ampere discov

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

red the first connection between electricity and magnetism with his discovery that an electr

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

c current produces a magnetic field. In 1831, Faraday extended this connection by discoverin

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

g that a changing magnetic flux produces an electric current in a loop of wire.

In 1864, Ma

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

well tied the whole theory of electricity and magnetism together with four equations. Among

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ther things, Maxwell's equations predict the existence of electromagnetic waves, oscillating

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

electric and magnetic fields which propagate at the speed of light. In fact, light itself t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rns out to be an electromagnetic wave. In 1887, Hertz produced the first radio waves and in

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

895, Marconi invented radio.

Electromagnetic theory eventually led to Einstein's discovery

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

of relativity. As a teenager, Einstein asked himself what it would be like to ride on a beam

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

of light. It was the consideration of this question which led him to stumble upon relativity

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Summary - Electricity and Magnetism

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