Summary - Relationships

Bob and Samantha were nice friends. They met in college through a common friend and instantly struck off a great rapport. They would often hang out with a gr

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

oup of buddies and had a great time together. A few months before departing from college, Samantha dropped some hints which made Bob wonder whether she was h

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rboring any special feelings for him. But it never occurred to Bob that he could ever get romantically involved with her. Eventually, it so happened, that Ti

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

, a childhood friend of Samantha, proposed her. Samantha was confused and asked Tim to give her three days so as to make up her mind. As Bob heard about this

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

he remained silent.

Finally Samantha made up her mind to accept Tim’s offer. In the next morning she got dressed to meet Tim. All of a sudden the doorbell

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ang and she received a flower bouquet delivered in her name. It has a note attached to it saying ‘Samantha-I am yours’- Bob.

Well, that was a nice romantic

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ove story. Thankfully, Bob had realized in time that Samantha was more than just a friend. I guess that many of us have encountered a similar situation at so

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e point of life. We all know that there is a difference between friendship and love, but when it comes to friendship with a person of opposite gender, we fai

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

to understand when we start developing a soft corner for that person. Instead of just enjoying her company we start craving for it.

Any romantic relationsh

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

p undergoes three stages. The first stage is the stage of infatuation. The other person impresses you. Her looks, her personality pleases you and you desire

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

o spend time with her. You desire to know her. Gradually you enter in the second stage, when you are really mad about her and she becomes a part of your life

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

without whom your life seems to be unnatural and gloomy. And ultimately you can not live without her and surrender yourself completely to love.

As I was sa

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ing, when friendship develops between a man and a woman, sometimes, there is a fragrance of attraction. And this attraction develops even if we are unaware o

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

it and even before we realize it culminates into deep love.

You may ask me ‘Do you mean to say that we can never have female friends?’ or ‘Does having a fe

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ale friend mean we are cheating our wives?’ No of course not. But it is essential for us to differentiate between friendship and infatuation.

Now you may as

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

me, how to do that? All I can suggest is that a friendship is an understanding, a rapport and of course one can not deny that there has to be a mutual likin

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

and trust for a friendship to sustain.

These are also some essential component for love. But in love there is one more important aspect which is ‘sacrifice

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

. Our love becomes complete when we can sacrifice everything for him/her. This is what separates love from friendship and all other emotions of life. So we c

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nclude that friendship can be a beginning of love, but it is not purely ‘love’. A true friendship can bring a smile at your face, but a true love can bring t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ars in your eyes.

As someone said, ‘sometimes a tear is more precious than a smile, because smiles are for everyone, but a tear is only for someone special.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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