Summary - Relationships

Q: What is a man's idea of helping out with housework?
A: Lifting his leg so you can vacuum.

"It's a wise husband who will buy his wife such fine china that she won't

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

trust him to wash the dishes." ~ Anon

Given a chance, most men will drink out of the juice bottle; will leave the food that goes in the fridge uncovered; will leave the vac

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

um cleaner in the middle of the living room; will leave the bed unmade; will not do the dishes; will leave the bathroom towel on the floor; will drop his pajamas on the floo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

and retrieve them untouched at bedtime; will put an empty icemaker back in the freezer, and so on and so forth. In general, these things mean practically nothing to them—th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ough I know many who are just the opposite.

One of my husbands was like this. It would drive me nuts that he would remove his PJs’ pants leaving them on the floor and in th

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

evening, would easily put them back on as if this was the most common thing in the world. I hated that because I was the one who had to pick them up, if I wanted them off t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e floor.

My other husband, on the other hand, was a cleaning freak, so to speak; only he would not move a hand to clean. Thank heavens we were in Brazil at that time and lu

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ckily had an assistant in charge of the household chores, the clothes and the cooking (i.e., a maid, for the less politically correct) who would then make sure that everythi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

g was spotless just as he liked them to be.

Now I think: well, if their behavior bothered me, shouldn’t I be the one to take care of this situation and stop nagging? Nowada

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s, my son leaves an empty icemaker in the freezer. What do I do? Tell him, please, to fill it with water before putting it back. Does he do this? Sometimes. When he doesn’t,

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

I will do it for him.

Now, a question remains: why am I so forgiving of my son whereas I was never forgiving of my life-partners? It dawned on me that the reason is pure an

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

d simple and it is called “unconditional love.” So now, if we are so indulgent with our children, as many of us are, it follows that, logically, we should be as forgiving w

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

th our men. After all, shouldn’t we love them unconditionally as well? Is there any other kind of love?

A Word of Advice:

Ladies: Put yourselves in their place. Who wants

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

o do things you are not cut off for? Have a heart and compromise.

Gents: If your spouse wants a neat house, why don’t you tell her do the cleaning and chores inside the hou

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

se and you will help out by doing other things outside of the home, such as fixing things when they break, taking the car for oil changes, etc.? Make it a fair arrangement.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

f course, you must share parenting.

Ladies and Gents: If both of you truly hate housework, inside and outside, stop bickering and hire help!

A story:
In Madrid… “Span

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

sh lawmakers introduced a new marriage contract this week that stipulates men must do half of the housework. The new vows will be used in civil marriage ceremonies starting

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

this autumn. Wives won’t be able to take their husbands to court for being lazy, but in case of divorce, a husband who has done less than his share will have to pay more ali

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ony. “Men have to learn to start taking more responsibility in the home,” said Margarita Uria, the member of the parliament who authored the bill, “and women have to help th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

m do it.” (The Week, July 1, 2005, p.8).

My two cents: Margarita Uria is just like I was: a total moron when it comes to understanding the opposite sex. And vindictive, too

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Summary - Know your Man: Messing Around

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