Summary - Relationships

Should you stay with your partner or leave them? Is all the pain you suffer in your relationship worth it for the good times you have together? Will it really be worth all the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

pain of leaving them or is it better to stay and stick it out?

In most relationships there comes a point when you have to decide whether your partner really has the qualitie

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

you need to stay together. Making the decision to stay or go is almost always a very painful and confusing time as there generally isn’t a quick fix or an easy answer to your

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

questions.

I have a friend in a fantastic relationship who taught me that if it’s hard work it’s probably not working. This was an alien concept to me. I come from a therapeu

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ic background which can sometimes promote the feeling that if it’s not hard work it’s not worthwhile. Years ago I made it my mission to figure out what made relationships work

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

; there seem to be two approaches – one more successful than the other!

Two Approaches to Relationships

The first is ‘don’t expect too much from your relationship and

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

it will work out just fine!’ Some things are always going to be problematic. So what if sex isn’t so important to one of you? So what if one party can’t be relied upon to keep

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

their agreements? So what if you never get to go on the holidays you really want to go on because your partner hates to travel? This may well work for some but it’s just not i

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

my nature. As far as I’m concerned, good enough just isn’t!

The second approach is to insist on great chemistry; to find a partner who isn’t perfect, but is perfect for you.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

The two primary areas you need to match up in are sexual chemistry and best friend chemistry. You’d think these two would be obvious to most people, but you’d be wrong. Peopl

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

make compromises on these points very early on and then wonder why they spend the rest of their lives hurting.

Great chemistry doesn’t mean it’ll be easy all the time - that

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

would be unnatural. It means that you’re excited and committed enough to work through the glitches as they arise rather than let them stack up. A stack of resentments is so mu

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

h easier to set fire to.

Working Out Whether to Leave

So the biggest piece of work I have clients do when they ask me to help them decide to stay or go is to get them

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to design their perfect partner. You may think this strange if you’re already in a relationship - but it’s just as valid now as it is when you’re single. So, what would be pe

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

fect for you?

The things you should focus on as you’re already in a relationship should be more emotional and behavioural in quality. Once you’ve sorted out what is perfect f

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r you, you can start to ask yourself questions about your current partner to see if they meet up to your ideal. Does your loved one treat you with the level of respect you exp

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ct? Is he affectionate enough for you? Does she make enough time for you? These aren’t necessarily questions that apply to you. Ask yourself the questions that matter to you o

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nce you’ve worked out what ideal is for you.

A couple more questions you may want to ponder - If twenty years from now your partner hadn’t changed in any significant way, wou

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d you still be happy as their partner? Would you consider your life together to have been more about adventure or more about endurance?

The strange thing is we often know wha

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the problems will be in a relationship many years in advance. The only question is, when will you handle them? We all know the longer you leave them the more painful it gets

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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