Summary - Relationships

As you button up your shirt, you ask, "So, what’s your diagnosis, doc?"

He pauses and then replies, "It appears you’re suffering from touch

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

deprivation."

Somewhat taken aback, you sputter, "Is there a special treatment for that?"

Smiling, the doctor answers, "Yes … lots and lots of hugs."

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

You heard the doctor. It’s time to reach out and touch someone. No excuses now. Today, January 21 is National Hugging Day!

This warm and

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

fuzzy holiday was created twenty years ago by Rev. Kevin Zaborney, of Caro, Michigan. One thing for certain, the man definitely chose the right time of

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

year for this holiday. Who wouldn’t want to cosy up to someone during such a cold, blustery month? Now although not officially a "national" holiday, ma

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ny embrace it all the same … with the other person’s permission of course.

The word "hug" has many definitions and is believed to have originated in Sc

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

andinavia, akin to Old Norse "hugga," meaning to comfort. Other definitions include an affectionate embrace or to clasp or hold closely. Whatever the de

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

finition, hugging is a gesture of love, of warmth, of caring … benefiting people both physiologically and psychologically.

Did you know that hugging in

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

creases the body’s endorphins (morphine-like substances in our blood and nervous systems), relieving us from pain and creating a mild euphoria? Medical

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

facilities and treatment centres across the globe are realizing its true healing value, and now use hug and touch therapy for the treatment of pain, dep

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ression and fear in their patients. One could almost say that hugs are natural painkillers.

Unfortunately, some researchers on the subject of hugging h

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ave revealed less favourable findings. For example, some studies show that children deprived of hugs during their infancy risk growing up incapable of l

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

oving others, suggesting that a child raised without any hugging can become a psychopath or sociopath.

Virginia Satir (1916-1988), noted psychotherapis

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t and family therapist, offered the best prescription when she advised, "We need 4 hugs a day for survival. We need 8 hugs a day for maintenance. We nee

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d 12 hugs a day for growth."

Many of us underestimate the value of hugging—the power of touch. Its effects are immediate, both the hugged and the hugge

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

r profit from the experience. And what is especially nice about hugging is that it’s not limited to only the hurting and the lonely … hugging is for eve

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ryone!

Top Ten Benefits of Hugging

Costs nothing
Boosts your immune system
Builds self-esteem
Foster

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s self-acceptance

Alleviates tension

Helps curb appetite

Saves heat

Is portable

Requires no speci

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

al setting or equipment

Feels incredibly good!

Wow, talk about benefits! Who wouldn’t want to celebrate National Hugging Day! Come

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

to think of it, why keep it to one day? Why not make every day a hug somebody day! Reach out and touch someone today … with their permission of course!

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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