Summary - Relationships

It is amazing the number of couples that allow the intimate side of their relationship slide. Loss of intimacy is one of those common marriage probl

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ems that eat away at the very foundation of a marriage turning what was once a loving and fulfilling relationship into nothing more than a shell.

T

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

he excuses are all too common, just too busy at work, the children are too demanding, we don’t have time or it’s just temporary to name but a few. W

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ith such easy excuses slipping off the tongue it’s just an open door for a myriad of marriage problems to take hold.

Like most common marriage prob

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lems if you are prepared to make an effort loss of intimacy in a marriage is relatively easy to resolve but the further apart you allow yourselves t

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

o grow the harder it is to get that marriage back on track.

It’s so easy just to say we don’t have the same feelings anymore and assume that the ti

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

me has come to draw the line but what about if you just take a step back and attack loss of intimacy in the same way you should handle any common ma

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

riage problem. Look at marriage issues as something to be resolved, a minor setback in life and not the end of the journey.

We all face problems at

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

work, with the children and with the family but work problems we handle, children issues we sort out and look how far we have to be pushed before w

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e even consider disowning our family. Why is it then so common for marriages to split up over a few solvable problems?

If we are prepared to make a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n effort with every other aspect of our lives why do so many couples just fall at the first hurdle? You can’t say that living with someone is someth

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ing we aren’t generally used to, after all we have to make allowances for others and cope with family differences as we grow up. What makes couple s

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

o what makes couples so blinkered, unbending and uncaring?

So many people loose site of their marriage vows, forget the bit about for better or for

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

worse and assume that as soon as the ring goes on their finger that their work is done. Marriage is never easy almost every marriage has its ups an

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

downs and letting the intimate part of the marriage slide is quite a common marriage problem. The couples that come out on top are those that recog

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

nise their failings, accept that some work needs to be done and refocus their attentions on what really matters.

To make a marriage work you need t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

hat special relationship time, people need to feel valued, respected, loved and that they are the most important thing in your life. You partner nee

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ds attention, the odd little gift, the kiss hello and goodbye, the fleeting caress and a cuddle at the end of the day. Never loose site of what is

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

important and if you’ve been sidetracked, which is a common thing to do, now is the time to take stock, sort out any marriage problems and get back

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

on the right track. You make time for everything else in your life so don’t become complacent with what matters most, your partner and your marriage

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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