Summary - Relationships

To deal with self-deceptions and lack of authenticity, our ego invents heroes, ideological heroes (men and women who hav

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e no dirty bits). Our ego compares who we are, and who our partner is, to these fantasy people we invented in our reacti

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ons to life. So, we start to complain because this lover in front of us is not like the dream we had, the ideal one, wit

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

h no dirty bits. Those heroes and heroines are invented because they avoid pain. I mean, who would fantasise about a boy

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

friend or girlfriend who caused us pain? But real people cause us pain. That is a guarantee. They will disappoint us for

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

sure. Many people fall in love with a fantasy, find out the fantasy is not real, and then fall out of love and blame th

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

eir partner.

Then we say, “I need to trust you” but really we are saying, “I need to see if you are the same as my fant

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

sy”. However, what we don’t know, what the ego doesn’t ever want to know, is that everybody has two sides. We are all ma

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

de of the same materials. We are not different, just different faces and bodies. So we want to fall in love with a fanta

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

sy to make the ego comfortable. Soon after that, if we don’t know how to be authentic, the honeymoon is lost because the

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

fantasy is spoiled. All this comes from having ideologies about people that are not real.

We can so easily judge ourse

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

lves, and our lovers, against some ideal. This usually relates back to our judgments on our parents. They are the key. I

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

f you can’t love your parents, you will not find love for yourself or your loved one. Unblocking love for one person is

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

unblocking love for every person and no one affects this equation more than your parents.

Love is to see bad things ha

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e good in them, and good things have bad in them. This is real love. Balanced perception. Neither infatuating nor resent

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ing your parents. They become irrelevant, their opinion does not affect you. Then you have truly grown up. Then your rel

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ationship with your beloved is not based on reaction to your parents, but on today, romance and true love. This is authe

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nticity, actually turning up ready to be in love. Your parents deserve your love, and this is how you release yourself t

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

o be in a sacred relationship. That is the day that trying to please them, worrying about their opinions becomes irrelev

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ant. You love them, you are free. What you give back, is done with love, not obligation or because of their expectations

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Do you remember about the Mouse and the Cheese story? Well.. I want to tell you about the story of mouse that always searching and smelling for their favorite cheese.

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