Summary - Relationships

Is your spouse too controlling? Are you too passive? Or are the roles reversed? Either way, if decisions in your marriage are normally a “tug of war” struggle and the same partner either almost

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

always wins or almost always gives in, then your marriage is being impacted by control issues.

Control issues refer to who’s in control, who’s in charge, or who’s getting their way. What’s at

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

stake is the power in the relationship and how differences are resolved.

It’s impossible to completely avoid all control issues in a relationship. Whether you have serious control problems in

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

our marriage will depend on the frequency and intensity of the control issues that arise.

But significant control issues are harmful to a relationship. Here are ten reasons you need to be conc

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rned if you have unresolved control problems in your marriage:

1. Control issues set up a parent-child relationship or dictatorship in the marriage. This shows a lack of trust and resp

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ect for the partner’s feelings, preferences, and judgment.

2. Relationships based on “one-up-man-ship” are constructed on the “winner-loser” model. This isn’t what you want to have in

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

healthy relationship. You want to create a “win-win” model.

3. The “winner” of the control struggle is viewed as “strong,” while the “loser” is viewed as “weak.” This dynamic isn’t he

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

pful to your relationship. It tears down your feeling of closeness and intimacy instead of building it up.

4. By stifling individuality and freedom, you run the risk of smothering and stif

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ing the very things that you value most—your spouse and your marriage. When one person makes the majority of the decisions, new ideas and honest feelings and reactions are suppressed.

5.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Control issues contribute to increasing the anger, resentment, and bitterness in the relationship. This is the natural spin-off of feeling disrespected or controlled by someone else.

6.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Thinking your mate should be just like you harms your relationship, as does viewing your mate as an extension of yourself. This squelches individuality and freedom and keeps your mate f

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

om living up to his or her potential.

7. Passive partners often become passive-aggressive when they are in a relationship with a more controlling partner. This gets in the way of hones

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

, direct communication. They “forget” to keep a promise to the spouse or conveniently sabotage the spouse’s efforts in some way.

8. An overly-controlling spouse sets up dynamics in the rel

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ationship that encourages the more passive partner to sneak around and hide things rather than risk confrontation. For example, a passive spouse may secretly phone a friend who she (or he)

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

knows the partner doesn’t want her to have any contact with.

9. Control conflict in a marriage encourages the game of “catch me if you can.” In this game, the passive partner tries to

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

efy or get around the controller’s rules. This can become a game of sorts within the relationship.

10. Unexpressed anger and resentment accumulate, and eventually the passive mate may rebe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

and decide there’s nothing to lose by becoming defiant or ending the marriage. This brings out the controlling tendency of the spouse even more, and his (or her) efforts to control the “re

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

bellion” make things worse. Any vestige of being on the same “team” is now gone, and the partners can feel like adversaries.

Trying to control your mate—actions, thoughts, feelings—will always

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

boomerang eventually and will have a harmful effect on your relationship.

It’s important to understand the relationship dynamics that are created when power and decision-making is out-of-balan

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e in a marriage. That’s the first step to becoming more aware and knowledgeable about the subject so that you can evaluate your relationship and decide if you need to make any personal changes

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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